Gameplay revolves around the use of the Nanosuit, which grants players a variety of abilities such as being invisible. The game's story serves as the end of the Crysis trilogy. Crysis 3's story revolves around Prophet, a Nanosuit holder who is on a quest to take revenge on the Alpha Ceph, the leader of the Ceph alien race.

The multiplayer portion of the game was developed by Crytek UK. It is the third main installment of the Crysis series, a sequel to the 2011 video game Crysis 2. Crysis 3 is a first-person shooter video game developed by Crytek and published in 2013 by Electronic Arts for Microsoft Windows, PlayStation 3, and Xbox 360.